RELAIX LAB
Consortia
Our team is developing a research program for the understanding and treatment of neuromuscular disorders. We are grateful to AFM-Telethon for the generous support of this program through the Strategic Pole Translamuscle.
We are active member of stem-cell-focused consortium: Labex-Revive,
Our research
The Relaix lab seeks to understand the fundamental mechanisms of development, regeneration and pathology, using skeletal muscle as a model tissue. Find out more.
Our lab is linked to UPEC Health Faculty, INSERM (Institut Mondor de Recherche Biomédicale), ENVA, EFS & APHP.
News
June 2025
Publication
Our study on "Extensive striated muscle damage in a rat model of Duchenne Muscular Dystrophy with Dmd Exons 10-17 Duplication" is out at Skeletal muscle
January 2024
Publication
Our study on "Generation of highly pure pluripotent stem cell-derived myogenic progenitor cells and myotubes" is out at Stem Cell Reports
September 2022
Publication
Our study on "Obesity impairs skeletal muscle repair through NID-1 mediated extracellular matrix remodeling by mesenchymal progenitors" is out at Matrix Biology
May 2025
Publication
Our study on "Forskolin treatment enhances muscle regeneration and shows therapeutic potential with limitations in Duchenne muscular dystrophy" is out at Skeletal muscle
March 2023
Publication
Our study on "Thyroid-stimulating hormone receptor signaling restores skeletal muscle stem cell regeneration in rats with muscular dystrophy" is out at Science Translational Medicine
April 2022
Publication
Our review on "The Notch signaling network in muscle stem cells during development, homeostasis, and disease" is out at Skeletal muscle
October 2024
Publication
Our study on "Progressive cardiomyopathy with intercalated disc disorganization in a rat model of Becker dystrophy" is out at EMBO Reports
October 2023
Publication
Our study on "Myopathologic trajectory in Duchenne muscular dystrophy (DMD) reveals lack of regeneration due to senescence in satellite cells" is out at Acta Neurop Commun
January 2021
Publication
Our study on "Cardiolipin content controls mitochondrial coupling and energetic efficiency in muscle" is out at Science Advances
Jan 2024
Publication
Our study on "Dual inhibition of P38 MAPK and JNK pathways preserves stemness markers and alleviates premature activation of Muscle Stem Cells during isolation" is out at Stem Cell Research and Therapy
December 2023
Publication
Our study on "Receptor interacting protein kinase-3 mediates both myopathy and cardiomyopathy in preclinical animal models of Duchenne muscular dystrophy" is out at J Cachexia Sarcopenia Muscle
January 2021
Publication
Our review on "Perspectives on skeletal muscle stem cells" is out at Nature Commun